The MarginGuide is a dedicated Raman spectroscopic device intended for assessment of tumor resection margins on resected tissue. Developed by RiverD, this technology is designed to support surgeons, pathologists and researchers with rapid, objective insight on the adequacy of the resection margins. By providing immediate feedback during tumor resection procedures, the MarginGuide supports more informed decisions without disrupting the surgical workflow.
Surgery is the treatment of choice for most solid tumors. Complete removal of the tumor is the aim. It provides the best prognosis and reduces the need for additional therapy. Unfortunately, the hands, eyes and experience of a surgeon often do not suffice to achieve this result.
The MarginGuide is designed to support surgeons at a critical moment in the surgical pathway: margin assessment. By combining rapid Raman spectroscopic measurements with a workflow-friendly design, the system offers clear and objective information on the location of inadequate resection margins that can be used immediately in the operating room, reducing the need of a second intervention later on.
The MarginGuide can be applied in both clinical and research settings where reliable assessment of tumor resection margins is essential. The system supports intraoperative guidance focused on improving surgical decision-making.
The MarginGuide enables systematic evaluation of resection surfaces directly after excision, allowing investigators to study tumor proximity at the margin in a controlled and reproducible way. The technology can also be used in the development and optimization of new surgical workflows and protocols, helping bridge the gap between research and clinical practice.
By combining rapid Raman measurements and a workflow-friendly design, the MarginGuide supports better-informed decisions at the moment they matter most: during the procedure itself.
Validation studies are currently underway for application of the MarginGuide technology in oral cavity cancer surgery, which is reported to have a very low percentage of adequate tumor resections.
We expect that the MarginGuide can be equally valuable to improve surgical treatment procedures for many other forms of cancer.
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